Ulrich Rant

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biophysical analysis biomolecular interactions electrically switchable nanolevers molecular dynamics fluorescence proximity sensing molecular ruler binding kinetics binding affinity protein diameter conformational change nuclease polymerase activity bispecific binders avidity melting thermodynamics multimers aggregation cell gene theraphies biotechnology research molecular interactions biosensors switchsense single-cell interaction cytometry scic biophysics kinetics association rates dissociation rates affinity conformational changes nucleic acid binding protein characterization automated workflows real-time monitoring drug discovery biologics development multiplexing fluorescence detection dual-color assays nanolevers dna nanotechnology protein-dna conjugates bi-specific antibodies enzymatic activity fluorescence resonance energy transfer fret biochemical assays spike protein interaction binders therapeutic antibodies molecular glue protein-protein interactions high-throughput analysis customizable biosensors assay flexibility high sensitivity detection automated analysis microfluidics research technology drug efficacy high-resolution kinetics cell membrane targeting biochip functionalization sample consumption efficiency real-time binding measurements surface plasmon resonance