Paul Bruno

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biotechnology research precision therapeutics allosteric modulators drug discovery platform small molecule therapeutics protein regulation disease treatment rare diseases precision oncology metabolite screening allosteric binding sites ai-based drug design drug design challenges clinical trials structural insights high value targets therapeutic approach pipeline development pharmaceutical innovation therapeutic areas oncology programs patient unmet needs bioinformatics clinical development drug candidates therapeutics for cancer small molecule inhibitors selective inhibitors pharmacology biopharmaceutical research enzymatic pathways metabolic disorders neurological disorders immune diseases therapeutic efficacy molecular targets experimental techniques biotech collaborations healthcare technologies drug resistance clinical trial recruitment fda approval process investigational drugs therapeutic outcomes disease mechanisms carcinogenic mutations metabolic vulnerabilities protein function restoration biotech industry leadership health care health wellness & fitness hospital & health care information technology & services biotechnology