Reza Mazhari

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biotechnology research activation lethality cancer therapeutics precision medicine oncogene overactivation targeted therapy drug resistance bioinformatics tumor growth selective killing first-in-class cancer medicines oncogenic pathways drug discovery clinical development genomics synthetic lethality tumor genetics pathway hyperactivation anti-tumor activity innovative oncology patient benefit cancer biology therapeutic targets functional genomics crispr regulatory approval biotechnology treatment paradigm advanced oncology cancer drugs mutation resistance therapeutic innovation cancer challenges high-throughput screening molecular pathways prevalent cancer types discovery pipeline oncology drug developers personalized medicine biomedical research cancer patient populations druggable targets clinical research therapeutic strategies tumor microenvironment cancer resilience novel cancer treatments information technology & services