Stefan Braam

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stem cells ipsc cardiomyocytes neurons drug discovery drug development cardiovascular safety cardiovascular efficacy neural safety neural efficacy cro fibroblast astrocytes electrophysiology safety pharmacology toxicology assay development contraction assays custom cell lines assay solutions disease modeling hts cmo biotechnology research induced pluripotent stem cells cell supply endothelial cells smooth muscle cells regenerative medicine custom ipsc services differentiation expansion screening assays functional assays biologics gene therapy rna therapy small molecule screening pharmacology neuroinflammation clinical success therapeutics customizable cell models elevated purity cells high-throughput screening multi-electrode array cell culture engineered cell lines vessel formation physiologically relevant in vitro models cardiac models cortical neurons toxicity assays translational medicine innovation in drug testing risk mitigation human disease modeling pharmaceutical industry therapeutic research assay capabilities early-stage drug development functional characterization custom assays cell type differentiation biotechnology ipsc technology cell therapy safety testing human disease models cardiovascular diseases neurological diseases scalable manufacturing biopharmaceutical companies therapeutic developers immuno-oncology gmp compliance predictive human biology client-centric approach strategic partnerships reproducibility cost-effectiveness clinical translation innovative therapies research & development tailored solutions project management scientific expertise productivity