Alexandre Fraichard

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genetically modified mouse rat & cell models knockout knockin point mutation humanization inducible systems etc crispr cas9 homologous recombination rmce targeted transgenesis offtheshelf catalog mouse models immunology immunotherapy oncology immunooncology license preclinical models cancer research fundamental research clinical research freedom to operate biotechnology research humanized mice immunodeficient rodents knockout models cell lines crispr/cas9 biopharmaceutical research gene editing in vivo efficacy translational research pharmacokinetics biologics assessment target-specific models therapeutic antibodies human immune system glp-1r mouse model t-cell engagers custom mouse models scientific validation oncology models metabolism studies disease progression drug delivery systems gene function analysis validation data biomedical research syngeneic models human cd34+ cells complex tissue models rag1 knockout hla-a2 transgene tumor microenvironment immune checkpoints immunocompetent mice tissue engineering humanization technologies drug efficacy testing metabolic disease models autoimmunity models transgenic mice biomedical applications pharmacodynamic assessment research collaboration biotech innovations life science solutions model generation services predictive models forwards compatibility fda compliance hospital & health care