Shakti Narayan

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biotechnology research cancer therapeutics small molecule inhibitors clinical trials atx-559 dhx9 inhibitor rna-modifying proteins biomarker-driven medicine precision oncology brca deficient cancer microsatellite instability msi-h deficient mismatch repair dmmr cell division chromosomal instability kif18a oncology drug discovery patient outcomes cancer treatment innovation translational research first-in-class therapies best-in-class drugs pharmacodynamics pharmacokinetics solid tumors treatment resistance fda clearance clinical advisory board anti-tumor activity mitotic kinesin health outcomes tumor vulnerabilities research collaboration life sciences cancer indications compassion for patients cancer biology first-in-human studies investigational new drug cancer drug development therapeutic targets drug optimization preclinical studies high unmet medical need clinical pipeline therapeutic modalities innovative cancer solutions health care health wellness & fitness hospital & health care