Michael Dabrowski

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target engagement drug discovery fee for service sub licensing translational science biomarkers cetsa selectivity assay development biotechnology research cellular target engagement preclinical studies target discovery lead optimization biomarker discovery high throughput screening target identification functional assays selectivity profiling mechanism of action in vivo target engagement hit confirmation lead generation proteomics lc-ms biologically relevant data therapeutic candidates translational studies biological insights compound profiling drug-target interactions chemical starting points protein-ligand binding unmodified cellular environments act as an extended team data-driven insights experimental validation custom assay development dose selection patient stratification unbiased view early off-target detection pathway discovery evidence-based clinical trials high-quality data assuring project progress specific study design cost-effective solutions pharmacological properties therapeutics development cellular pathways data generation scientific commitment collaboration cutting-edge technology streamlined workflow actionable insights marketing & advertising sales