Heidi Jones

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induced pluripotent stem cells hepatocytes pancreatic cells disease modelling drug discovery toxicity testing inherited metabolic diseases screening crispr gene editing hittolead donor variance panel intestinal organoids biotechnology research ipsc disease modeling toxicity screening cell-based assays gene editing crispr metabolic diseases efficacy screening ulti-hep wild-type cells hepatocyte models toxicity prediction biotechnology contract research organizations bioassay services in vitro models liver disease hepatocyte differentiation clinical translation patient-derived cells phenotypic screening mechanistic insights therapeutic development disease-specific models a1atd wilson's disease urea cycle disorders scalable cell production cellular models high-throughput screening gxp compliant pharmaceutical research metabolic dysfunction-associated steatotic liver disease liver function assays custom model development regulatory compliance live plate format hydrogel-encapsulated cells long lifespan cultures batch-to-batch consistency glycogen storage disease collaborative r&d contract research services