Dethardt Muller

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biotechnology research anti-cancer immunotherapy innate immune response adaptive immune response arenavirus therapy tumor microenvironment immune evasion t cell activation tumor antigen presentation cancer treatment immunostimulatory approach systemic administration tumor regression metastasis control immune cell influx drug candidates clinical trials preclinical studies cgmp manufacturing targeted therapy immune activation novel therapeutics payload-carrying therapeutics cancer immunotherapy tumor cells immune system engagement oncolytic therapy safety profile distant metastases specific cancer indications solid tumors virotherapy cancer pipeline infectious agents antigen-presenting cells t cell infiltration immune surveillance persistent inflammation r&d funding medical need biomedicine viral infection immuno-oncology drug development scientific research clinical evaluation healthcare innovation health care health wellness & fitness hospital & health care